About Antidepressants

Antidepressants are medications that work on neurotransmitters (chemicals that one nerve uses to communicate with other nerves). By increasing the amount of these compounds that circulate in the brain, these medications are able to relieve symptoms of depression and anxiety for many people. In addition they have multiple other uses including the treatment of social phobias, obsessive compulsive disorders and a variety of other problems. They are not addicting, although some must be tapered to avoid withdrawl symptoms. They usually require three to four weeks to work, sometimes longer. We commonly use them for six to twelve months minimum. Thus far no problems have been found with long-term use of antidepressants.

There can be interactions between antidepressants and other medications, so it is a good idea for us to discuss your medications when we start them or if another doctor prescribes new medications for you. The most common kind of interaction is that the antidepressant can change the way your body metabolizes another drug, potentially making it stronger or weaker.

In general antidepressants are very safe. Minor side effects are not uncommon and often decrease with time. Let me know if you are experiencing severe or unusual side effects. Sometimes we need to switch medications. If I am not available, ask to speak with the clinic nurse, Gail Fahey, R.N., or Rita Perotti. Also the pharmacist can help with questions about medications.

Here is a list of some common side effects:

• Upset stomach - This can be minimized by taking the medication with food.
• Headache - If this happens to you, try taking some aspirin, tylenol, or motrin.
• Vivid dreams - most patients ignore this.
• Nervousness or problems with sleep - Let me know if this happens. We can often solve the problem by decreasing your dose but may need to change medication.
• Decrease in sex drive or change in sexual performance - Again, tell me if this is a side effect that is bothering you. The are are a few things we can try to deal with this problem.
• Sensitivity to the sun - It is best to wear sunscreen if you are taking antidepressants. Some people are much more likely to sunburn while they take the medications.

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